How Cholesterol Lowering Drugs Lowering Can Harm Your Health

Over 45 million Americans and millions more worldwide are currently taking cholesterol lowering drugs. Most of them are completely unaware of the adverse and preventable side effects that cholesterol lowering drugs, also known as statin drugs, are associated with, in particular,decreased heart muscle function, increased risk of developing diabetes, cognitive decline, and memory loss. These drugs are linked to muscle damage, weakness and a breakdown of muscle fibers resulting in the release of muscle fiber contents into the bloodstream.

Statin drugs are very toxic because they prevent cells from producing a key vitamin, CoQ10, which causes the side effects. Relatively low doses of statin drugs such do lower cholesterol levels. These drugs function by halt an enzyme that changes the chemical HMG-CoA to mevalonate, which is an early and limiting step in cholesterol production. This part of the cholesterol pathway in animal cells leads to the development of CoQ10. Also, statin drugs can reduce CoQ10 in the liver and lowers at doses prescribed by physicians.

Unfortunately, most doctors are unaware of the cause of these complications, and could recommend taking CoQ10 supplements to their patients when prescribing these drugs. Pharmaceutical company even has a patent on the drug and CoQ10 combination, since but never released it. In 1989, Merck& Co., makers of lovastatin was awarded patent #4,933,165.

The patent notes that Coenzyme Q10 is a component in the respiratory chain and is present in every cell having mitochondria. It is thus an essential co-factor in the generation of metabolic energy and is particularly critical in muscle function.

Researchers, determined the levels of Coenzyme Q10 in heart tissue biopsy samples taken from patients with varying stages of damage to the heart muscle. They discovered lower tissue levels of CoQ10 are associated with increasing severity of the symptoms of cardiac disease. Unfortunately, the FDA doesn’t warn consumers of this dangerous and reversible side effect.There are no official warnings in the U.S. regarding CoQ10.

In comparison to the U.S., Canada requires labeling and clearly warns of CoQ10 depletion and even notes that this nutrient deficiency “could lead to impaired cardiac function in patients with borderline congestive heart failure.”

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The Benefits Of Vitamin D

This vitamin is fat soluble and has been the center of attention in recent years. Vitamin D helps bones in absorbing calcium in the small intestines and is essential for bone growth and maintaining bone density.

Numerous studies have proposed that vitamin D 3 is absorbed better and is more effective in increasing and maintaining the vitamin D level in the blood.

The best way to diagnose vitamin D deficiency is to measure 25 (OH)-D and not 1, 25 (OH)-D. It has been suggested that improving vitamin D levels in healthy individuals can boost immunity and help to lower the risk of autoimmune diseases, cancers, cardiovascular diseases, etc.

The researchers have also suggested that increasing daily dietary vitamin D intake decreases the likelihood of developing Alzheimer’s disease.

Sunscreen could decrease the absorption of UV-B and subsequently cause a lower level of 25-OH-D. For instance, sunscreen with a sun protection factor (SPF) of 8 can drop vitamin D3 synthetic capacity by 95%, and SPF 15 can cut it by 98%.

There have been puzzling endorsements in past years from different organizations about the amount of vitamin D necessary to prevent deficiency, including the recent U.S. Preventive Services Task Force conclusion that the benefits and harms of daily supplementation with larger than 400 IU of vitamin D3 and greater than 1,000 mg of calcium to avert fractures are not clearly understood.

A recent research study has found that the amount of vitamin D varies from 9% to 146% of the amount recorded on the label. Only one thirds of the tested sample of supplementary pills met the US Pharmacopeial (USP) Convention standards.

According to the US Pharmacopeial (USP) Convention standards, compounded pills of vitamin D supplements should contain 90% to 110% of the active ingredient. However, the Food and Drug Administration (FDA) does not regulate the vitamin D supplements. The accurate amount of nutrients in these pills is not measured before they hit the market.

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Why is Cholesterol Needed by Our Body?

Most people think that cholesterol is an unwanted and harmful substance inside the body. They believe that cholesterol is damaging to one’s health, and which the body’s cholesterol range must be decreased as much as possible. In actual fact, this perception is merely partly correct. Cholesterol plays some purpose throughout the body that happens to be critical to properly function. Unfortunately, too much cholesterol can be unhealthy with regard to a person’s overall health. Everybody must manage their cholesterol at a proper range and one really should completely focus on preserving cholesterol levels at the preferred range, and not really on shedding cholesterol from the body.

So what is cholesterol?

Cholesterol is essentially a kind of fat or lipid, which happens to be important for the body to efficiently function. The surface layer of each and every cell of the human body is made of cholesterol. This fat is basically released by the liver.

The primary functions of cholesterol

Virtually no human body cell may be created without the need for cholesterol in its exterior layer. As with digestion, the human body needs bile, a particular type of fluid made by the liver; and bile cannot be produced without cholesterol.

For people who absolutely love the outdoors, they would never benefit from it without cholesterol in the body. Without cholesterol, the human body won’t be able to generate vitamin D via the sun light it absorbs. Many significant hormones also are released with the aid of cholesterol, which includes the estrogen and androgen sex hormones. Cholesterol is also needed for the effective assimilation of vitamin A, E and K. For this reason, we simply just are unable to completely purge cholesterol.

Various forms of cholesterol:

The first type of cholesterol, Low Density Lipoproteins (LDL), is oftentimes known as the “bad cholesterol”. This particular “bad cholesterol” is also used by the body to certain benefit. However, in the event that LDL cholesterol levels become excessive, then there will be a raised possibility of developing heart-related challenges as well.

The second type of cholesterol, High Density Lipoprotein (HDL), is also known as the “good cholesterol”. HDL cholesterol helps remove excessive LDL or “bad cholesterol” in the body. Hence, HDL cholesterol works to lower the probability of developing heart related health challenges.

Triglycerides, the third form, are essentially chemical forms containing fat or cholesterol. The amount of food or calories any person takes each day is not always totally utilized by the body. The unused portion of foods or calories are turned into triglycerides by the body and retained. When the body needs energy, these triglycerides are spent as an alternative supply of energy.

Appropriate cholesterol levels:

For people in great health, total cholesterol level under 200 mg/dL is regarded as being normal. But for individuals with a greater risk of heart-related conditions, medical practitioners frequently suggest sustaining a lower cholesterol level.

Visit your doctor and ask to have your cholesterol level checked. It is the only way to know your cholesterol profile. When you know your cholesterol level, try to find a cholesterol chart that can give you an assessment using a combination of your LDL, HDL and Triglyceride count.

Categories Connected by Heart Murmurs

Heart murmur is a condition, which was examined frequently. Scientists have agreed that the majority of the presentations of this state are generally benign, and should be no motive for alert. Logically, there are exclusions, exactly like with anything else, but they’re very rare. The condition can be located most frequently at children, and because of this , from birth, they’re subject of check-up. There is a system that classifies the different presentations of a heart murmur. Here, we will speak about this, and even exactly how different interventions have interaction with that typical ailment.

The Category System of Heart Murmurs

Presently there are seven distinct elements which might assist professionals discern one form of murmur from the next. According to formal resources, they are the following – timing, form, place, the radiation, strength, pitch and quality. All these elements may serve to discover the precise factor stimulating the present murmur. Utilising substantial check methods, practitioners are able to specify every single characteristic singularly and assess its stage. According to this evaluation, it may be discovered whether the murmur is actually benign or not. Using this classification, we can even realise whether the murmur is caused by a hereditary defection or perhaps by a new ailment.

The timing of the murmur is split up into two groups – systolic and also diastolic. Both of these are actually influenced by the time inside which the murmur is in fact noticed. By systolic conditions, it’s observed through the process of clenching of a heart muscle tissue whereas diastolic conditions are actually known for sound noticed over the release. Both are determined by using basic mnemonics.

The shape of a murmur is actually determined by how an intensity changes over time. The intensity might be increasing or maybe decreasing within a specific period. The particular characteristics are respectively identified as crescendo and decrescendo. There is a middle case, however, causing a crescendo-decrescendo constant murmuring of the heart.

The location of the murmur is most simply classified. There are actually six distinct areas in the chest, each connected with a corresponding part of the heart. By listening to them the murmur can quickly become located. In that way the specialist can identify where exactly the murmur is situated. The several parts of the heart in which the murmur could be sensed talk about distinct conditions. This really is one of the most trustworthy practices utilised for classification of the murmur. Because of this , most experts are going to go for it initially on top of everything else.

Generally there is the specialized characteristic connected with the location of a murmur, which is termed radiation. It is actually connected with the point that the noise of the murmur radiates in the different way, according to where it is based. The most typical case is that, in which the murmur radiates in the exact same direction as the blood flow. Though, there are well-known exclusions that might in fact talk about more dangerous disorders present.

Intensity is probably the most severe characteristics to look out for. Generally, it isn’t good for a murmur to be either too quiet, or perhaps too loud. Both options might speak of awful health of a heart. Though, intensity definitely ranges in different scales, usually measured in 6 different levels. The 1st stage is when the murmur is almost completely indistinguishable, and the practitioner might need to invest quite a long time listening through a stethoscope. Although, the 6th level is so noisy that you simply need to put it above the body to comprehend that the murmur exists. Intensity is proven to show benign murmurs greatest in the center ranges on the scale.

Pitch can be quite similar to the expression used in music. The murmur is going to have a distinct and tense pronunciation of tone. It might be categorised as small, medium and high easily, as even the inexperienced ear will certainly sense the distinction. A different pitch will always show another type of disorder. It’s recorded that the middle pitch shows benign murmurs most commonly.

Quality is the last among the classifications related with a heart murmur. It should be said that this isn’t an necessary characteristic. Quality speaks of only abnormal characteristics present in the sound of the heart. These can involve hard, blowing as well as musical murmurs, that are all very specific and also talk about certain severe heart disorders. If the quality specification is actually observed, then that means that the murmur is going to need specialized treatment method.

Interventions

Occasionally, a murmur can’t be identified easily. There might be distortion, or maybe the murmur could have so low intensity, that it is totally unheard. For this, you will discover various interventions, which the practitioner may employ to acheive a much better hearing of a murmur. Amongst the simplest and most typical interventions is, to place the person in the special pose. Like this, the practitioner will make a murmur become more clear and evaluate it most closely. Some other interventions could contain execution of certain firmly professional medical interactions.

Conclusion

The murmur could be a common disorder, but it is vital that we look at it strongly to determine if some other issue exists. Regarding that, the modern classification method functions flawlessly. Every single cardio-related doctor is going to know various specifications connected with a murmur, in order to be capable of discern it promptly. A few of these ailments could progress, which may lead to fatal consequences. This is why you should get checked out on a regular basis, specially if, you’ve past experience with heart murmurs.

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Treating Hypertension with Diet

A healthy diet is essential regardless of an individual’s cardiovascular risk profile. Many studies, including Dietary Approaches to Stop Hypertension (DASH), have provided evidence of the heart and vascular benefits of specific dietary guidelines.

An early modification in dietary preferences may prevent and/or improve high blood pressure, high cholesterol, and subsequently other health-related difficulties.

If a rise in blood pressure with age could be prevented or diminished, many conditions, such as high blood pressure, heart, vascular and kidney disease, and stroke, could be prevented.

Sodium: The leading source of sodium in Western diets is processed food, for example, extreme quantities of salt are added in packaged food and in food eaten in restaurants. The DASH trial evaluated the effects of sodium intake in addition to the DASH diet and established that lowering sodium intake shrinks blood pressure levels.

At this time, mean sodium intake of the population is approximately 4,100 mg per day for men and 2,750 mg per day for women, 75% of which derives from processed foods. According to the guidelines dietary sodium should be reduced to no more than 100 mmol per day (2.4 g of sodium).

Alcohol: Alcohol consumption should be restricted to no more than 1 oz (30 mL) of ethanol, the equivalent of two drinks per day for most men and no more than 0.5 oz of ethanol (one drink) per day for women and lighter-weight persons. A single drink is equivalent to 12 oz of beer, 5 oz of wine, or 1.5 oz of 80-proof liquor. Modest alcohol intake can lessen systolic blood pressure by 2-4 mm/Hg.

Alcohol intake should be limited to no more than two drinks per day in most men and no more than one drink per day in women and lighter-weight persons.

Caffeine: Caffeine may cause high blood pressure; though, this outcome is frequently transitory. Sensible ingestion of caffeine per day does not considerably raise blood pressure. Coffee intake should be fewer than two cups per day.

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Triglycerides: Important Facts

Majority of individuals are accustomed with cholesterol but few are knowledgeable about triglycerides. Elevated triglycerides are an important risk factor for heart disease regardless of so-called bad cholesterol Low Density Lipoprotein [LDL]) and other well-known risk factors.

Similar to elevated levels of fasting triglycerides, very high levels of non-fasting triglycerides may also increase the risk for coronary heart disease. There is growing interest in assessing triglycerides in individuals who have not fasted. The reasoning is that a non-fasting level of triglycerides may be more characteristic of the typical circulating level of triglyceride. Since majority of the day blood lipid levels reflect a non-fasting level.

High triglyceride is the third leading cause of acute pancreatitis after gallstone disease and alcohol. A triglyceride molecule is a combination of three molecules of fatty acids plus glycerides. It is the most common form of fat that humans digest. Changes in lifestyle habits are first-line therapy for all lipid disorders, including elevated triglycerides.

A regular exercise schedule consisting of at least 30 minutes of moderately intense physical activity (e.g., brisk walking), smoking cessation, and restriction of alcohol use and avoidance of high carbohydrate diets could help to reduce triglyceride levels in blood.

Individuals with high blood glucose level or unregulated diabetes may have higher blood triglyceride level. Certain drugs like corticosteroids, protease inhibitors for HIV, beta blockers, and estrogens may increase blood triglyceride levels.

The American Heart Association, the US Department of Agriculture, and Health and Human Services endorse regular intake of fatty fish (salmon, tuna, herring, sardines, mackerel, and trout) that deliver omega-3 fatty acids (docosahexanoic acid [DHA] and eicosapentaenoic acid [EPA]).

Intake of 8 ounces of fatty fish in 7 days offers an average of nearly 500 mg/d DHA and EPA.

Treatment consisting of 4 g of omega-3 fatty acids per day resulted in a median reduction of triglycerides of almost 45%. For patients who have severe hypertriglyceridemia (equal or greater than 500mg/dl), therapeutic options recommend lowering triglycerides by including in the patient’s diet 4g/d omega-3 fatty acids, fibrates, high doses of niacin and, if needed, high doses of statins.

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